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In September 2024, the World Health Organization (WHO) released new guidance on preventative treatment for tuberculosis (TB). Thanks to new evidence from two randomised controlled clinical trials, the WHO now recommends that contacts of people with multidrug-resistant TB take six months of daily levofloxacin.
In this episode of the Trial Talk podcast, we find out more about the TB-CHAMP and VQUIN trials. We also learn how the teams came together to combine their data and strengthen their evidence, using new statistical methodologies developed at the MRC Clinical Trials Unit at UCL.
The episode features interviews with Anneke Hesseling, Principal Investigator for TB-CHAMP, based at Stellenbosch University, and Trinh Duong, based at the MRC CTU at UCL, the trial statistician for TB-CHAMP and lead for the combined data analysis with VQUIN.
8
9/23/2024
Every year on 1st December, we mark World AIDS Day to show solidarity in the fight against HIV and AIDS, and to remember those who have sadly lost their lives.
Since the start of the global AIDS epidemic in the 1980s, researchers have made enormous progress towards preventing HIV transmission, and treating those who are living with HIV so that the virus remains suppressed. But while there have been marked improvements for adults, treatment coverage in children and adolescents is lagging behind.
In the second of our World AIDS Day episodes, we highlight the important role that young people living with HIV play in research, by shaping clinical trials to better serve the needs of their community.
This episode features Lungile Jafta, who works closely with young people through Penta’s youth engagement programmes, and Gugu, a former Youth Trials Board member from South Africa who is living with HIV.
4
11/30/2023
Every year on 1st December, we mark World AIDS Day to show solidarity in the fight against HIV and AIDS, and to remember those who have sadly lost their lives.
Since the start of the global AIDS epidemic in the 1980s, researchers have made enormous progress towards preventing HIV transmission, and treating those who are living with HIV so that the virus remains suppressed. But while there have been marked improvements for adults, treatment coverage in children and adolescents is lagging behind.
In the first of our World AIDS Day episodes, Dr Anna Turkova, Clinical Principal Research Fellow at the MRC Clinical Trials Unit at UCL, and Philippa Musoke, Professor of Paediatrics and Child Health at Makerere University, explore the reasons for these disparities and how the MRC CTU at UCL is working to close the gap between adults and children through clinical trials.
1
11/30/2023
Lunch Hour Lectures - Spring 2011 - Episode 13: Stabilising the global population: Where next for the Millennium Development Goals for health and nutrition?
In many poor countries the Millennium Development Goals for improvements in nutrition and health, especially of mothers and children, will not be met by the target date of 2015. This talk will review progress towards these targets and consider critical obstacles to success. New strategies will be considered to improve nutrition and to accelerate reductions in death and fertility rates so that the global population will be stabilised by mid-century.
Vintage Podcasts - Lunch Hour Lectures
9
9/29/2023
A conference on Closing the Gap in a Generation: Health Equity through Action on the Social Determinants of Health 6-7 November 2008, London.
Commission on the Social Determinants of Health.
3
3/11/2021
A conference on Closing the Gap in a Generation: Health Equity through Action on the Social Determinants of Health 6-7 November 2008, London.
Commission on the Social Determinants of Health.
12
3/5/2021
The annual UCL–Lancet Lecture was delivered on 29 November 2009 by Professor Lord (Robert) May, former Government Chief Science Adviser and former President of the Royal Society. Professor Lord May’s lecture was entitled 'Climate Change: The biggest global threat of the 21st century?' The event was organised by the UCL Institute for Global Health, the hub which brings together UCL’s multidisciplinary wealth of intellectual capital and international collaborations to provide innovative, workable solutions at scale to address the Grand Challenge of Global Health.
Professor Lord (Robert) May, Zoology, Oxford University.
Event Date: 29 November 2009
Publish Date: DEC 8, 2009
11
3/1/2021
The annual UCL–Lancet Lecture was delivered on 29 November 2009 by Professor Lord (Robert) May, former Government Chief Science Adviser and former President of the Royal Society. Professor Lord May’s lecture was entitled 'Climate Change: The biggest global threat of the 21st century?' The event was organised by the UCL Institute for Global Health, the hub which brings together UCL’s multidisciplinary wealth of intellectual capital and international collaborations to provide innovative, workable solutions at scale to address the Grand Challenge of Global Health.
Professor Lord (Robert) May, Zoology, Oxford University
Event Date: 29 November 2009
Publish Date: DEC 8, 2009
5
2/23/2021