In September 2024, the World Health Organization (WHO) released new guidance on preventative treatment for tuberculosis (TB). Thanks to new evidence from two randomised controlled clinical trials, the WHO now recommends that contacts of people with multidrug-resistant TB take six months of daily levofloxacin. In this episode of the Trial Talk podcast, we find out more about the TB-CHAMP and VQUIN trials. We also learn how the teams came together to combine their data and strengthen their evidence, using new statistical methodologies developed at the MRC Clinical Trials Unit at UCL. The episode features interviews with Anneke Hesseling, Principal Investigator for TB-CHAMP, based at Stellenbosch University, and Trinh Duong, based at the MRC CTU at UCL, the trial statistician for TB-CHAMP and lead for the combined data analysis with VQUIN.

8

9/23/2024

Lunch Hour Lectures - Autumn 2009 - Episode 4: The challenge of HIV refuses to disappear Deenan Pillay Professor of Virology Head, Department of Infection, UCL Programme Director, Infectious Diseases, UCL Partners Vintage Podcasts - Lunch Hour Lectures

2

7/25/2023

Although human DNA is 98 per cent similar to that of the chimpanzee, the infections we catch are 80 per cent different. Most are new acquisitions that we have picked up as humans spread across the world. In fact, pandemic infections like smallpox and influenza only date from the last 12,000 years or so after we formed settled farming communities and later developed large colonies known as cities. Does the history of infectious diseases help to predict future epidemics?

4

4/21/2021

Although human DNA is 98 per cent similar to that of the chimpanzee, the infections we catch are 80 per cent different. Most are new acquisitions that we have picked up as humans spread across the world. In fact, pandemic infections like smallpox and influenza only date from the last 12,000 years or so after we formed settled farming communities and later developed large colonies known as cities. Does the history of infectious diseases help to predict future epidemics?

45

2/26/2021

i-sense is an interdisciplinary project led by Prof. Rachel McKendry,working on engineering a new generation of agile and globally impactful early warning sensing systems for infectious diseases and antimicrobial resistance. The video describes some of i-sense's technologies, applications and working with end-users.

82

6/30/2020

On Episode 2 we talk about things that transfer from one place to another. Discover how traces of DNA can transfer onto things you’ve never touched, leading to wrongful convictions. Hear about future technology that will send information on light waves rather than radio waves, and learn how antiretroviral drugs prevent the transmission of HIV between partners. Join our host, Suzie McCarthy, as she explores these topics with Professor Ruth Morgan, Professor of Crime and Forensic Sciences in the Faculty of Engineering Sciences; Dr Paul Haigh, a visiting lecturer and a former senior research associate within the Communications and Information Systems Group; Professor Alison Rodger, Professor of Infectious Diseases and consultant at the Royal Free London NHS Foundation Trust, and Simon Collins, HIV positive treatment advocate at I-Base, an organisation that provides information about HIV treatment to HIV positive people and healthcare professionals. www.ucl.ac.uk/made-at-ucl

17

11/13/2019

As a clinically-trained academic in public health and infectious disease epidemiology, Prof Sonnenberg’s research career has focused on areas of public health priority: TB/HIV, sexual health and STIs. In her Inaugural Lecture, Pam sheds light on her journey from a South African medical student to a leader of multi-disciplinary research teams, with the consistent aim of making a difference.

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11/4/2019