Lunch Hour Lectures - Spring 2011 - Episode 5: Genetic testing in the 21st century: Should we screen the human embryonic genome before implantation? In preimplantation genetic diagnosis (PGD), embryos are created by IVF and cells removed from these embryos for genetic analysis. Until recently, testing was solely for the disease the couple carried. The use of array-comparative genomic hybridisation and single nucleotide polymorphism arrays has entered the PGD arena. These techniques allow all chromosomes and many genes to be examined. The analysis of the whole genome prior to implantation brings ethical concerns. Will healthy couples opt for PGD to select their ‘best’ offspring? Vintage Podcasts - Lunch Hour Lectures

5

9/20/2023

The pro-screening lobby is locked into a mindset dating back to the late 1980s. Since then our understanding of the biology of breast cancer and its treatment has moved on whilst the screening programme continues without modification based on the results of trials reported in 1987. This lecture will discuss some of the harmful problems of this over-diagnosing system, and will look at the need for radical change to bring the entire programme up to date with modern practice based on risk assessment and risk management. Lunch Hour Lecture by Professor Michael Baum.

235

3/11/2021

The pro-screening lobby is locked into a mindset dating back to the late 1980s. Since then our understanding of the biology of breast cancer and its treatment has moved on whilst the screening programme continues without modification based on the results of trials reported in 1987. This lecture will discuss some of the harmful problems of this over-diagnosing system, and will look at the need for radical change to bring the entire programme up to date with modern practice based on risk assessment and risk management. This lecture marks Breast Cancer Awareness Month. Lunch Hour Lecture by Professor Michael Baum.

87

2/25/2021