All Categories
 
Categories
Tags
clinicaltrials X
 
   
8 items found in 1 pages
Octopus (part 2): Introducing the trial with Jeremy Chataway
Octopus is a new clinical trial for people living with progressive multiple sclerosis (MS), which is designed and run by the MRC Clinical Trials Unit at UCL. Thanks to its multi-arm multi-stage platform design, Octopus has the potential to transform the way treatments for progressive MS are tested. The trial is now open in the UK and will be recruiting participants for the next few years. The podcast mini-series will explore the trial from different perspectives by talking to neurologists, MS experts and people affected by MS. Part 2 of the series explores our Octopus trial in depth. Professor Jeremy Chataway, lead investigator of Octopus, discusses its novel design, the treatments it will test, and the criteria for people to take part. He also explains the data researchers will collect and analyse to find out if a treatment is working.
1
10/24/2023
Episode 9 (part 1): Octopus: The multiple sclerosis landscape with Jeremy Chattaway, Dawn Lyle and Matthew Justin
Octopus is a new clinical trial for people living with progressive multiple sclerosis (MS). Thanks to its multi-arm multi-stage platform design, Octopus has the potential to transform the way treatments for progressive MS are tested. The trial is now open in the UK and will be recruiting participants for the next few years. The podcast mini-series will explore the trial from different perspectives by talking to neurologists, MS experts and people affected by MS. Part 1 covers the treatment and research landscape of MS and the challenges of treating progressive MS. It features Jeremy Chataway, neurologist at National Hospital for Neurology and Neurosurgery at UCLH and Professor of Neurology at UCL, who is leading the Octopus trial. We also hear from Dawn Lyle, Lead Research MS Nurse, and Matthew Justin, MS Specialist, who are based at the Anne Rowling Regenerative Neurologic Clinic in Edinburgh.
4
10/19/2023
How can clinical trials make the most of healthcare systems data?
Running a clinical trial means collecting a lot of data from the trial participants. But some of this data might be collected and stored in healthcare systems, as well as in clinical trial case report forms. What if we could avoid this doubling up, save time and resources, improve recruitment and reduce missing data? In this episode we explore the opportunities and challenges of using healthcare systems data in clinical trials, with Dr Macey Murray and Professor Matt Sydes. Resources: British Heart Foundation Data Science Centre webinar (Macey Murray) - www.youtube.com/watch?v=OzQeMUUG7tQ How to get your own crocheted duck - twitter.com/drmakerbaker/status…22224971419665?s=20 For more questions or feedback on the series, contact us at mrcctu.engage@ucl.ac.uk For more information and access to the transcript of this episode: bit.ly/3NKtKjs
1
6/26/2023
Neonatal infections (part 2): How the NeoSep1 trial will help treat sick newborns
Neonatal sepsis is a life-threatening infection that affects up to 3 million babies per year globally. In an effort to identify better treatments, the NeoSep1 clinical trial evaluates new antibiotic combinations for newborn babies with sepsis. To learn more about the trial, we speak to Adrie Bekker and Cristina Obiero, principal investigators of the trial in South Africa and Kenya, Reenu Thomas, a neonatologist from South Africa, and Francesca Schiavone, the clinical project manager of the NeoSep1 trial in London.
1
6/8/2023
Neonatal infections (part 1): The NeoOBS study and the global challenge of neonatal sepsis
214,000 newborn babies die of sepsis caused by infections that are resistant to antibiotics every year. This is a major problem worldwide, but disproportionally affects low- and middle- income countries. Reenu Thomas and Adrie Bekker, two neonatologists from South Africa, and Francesca Schiavone, clinical project manager at the MRC CTU at UCL in London, discuss the challenges of treating neonatal sepsis and present the results from an observational study (NeoOBS), which assessed mortality rates of babies with sepsis.
2
5/17/2023
EURO EWING Consortium - an exemplar for building European collaborative research for a rare cancer (subtitled)
EURO EWING Consortium - an exemplar for building European collaborative research for a rare cancer (subtitled)
80
10/20/2020
First results of the Euro Ewing 2012 trial comparing two chemotherapy regimens in newly diagnosed Ewing sarcoma
First results of the Euro Ewing 2012 trial comparing two chemotherapy regimens in newly diagnosed Ewing sarcoma
243
10/15/2020
rEECur - new frontiers, building an evidence base in recurrent Ewing sarcoma
rEECur - new frontiers, building an evidence base in recurrent Ewing sarcoma
180
10/15/2020