To mark World Haemophilia Day, we sit down with Professor Amit Nathwani of the UCL Cancer Institute to explore his journey to commercialising the groundbreaking haemophilia A treatment, Roctavian.
Host Nigel Campbell is joined by Prof Nathwani and Dr. Rick Fagan, UCLB Director of Biopharm, to explore how Amit’s work looking after patients with haemophilia in the NHS instilled a mission to develop a 'one and done' vaccine type approach to the condition.
Amit’s lab to market story, working with UCLB, led to the creation of Roctavian, a one-time gene therapy used for the treatment of adults with severe haemophilia A. The therapy, which was licensed to BioMarin Pharmaceutical Inc, received marketing approval in Europe in 2022 and US FDA approval in 2023, and is now available to patients commercially.
4
4/15/2024
This episode we explore Positive Impact. UCLB is helping to create a new generation of businesses from UCL academics specifically with positive societal impact at their heart. The commercialisation process can be a long road requiring financial, legal, and practical support.
Nigel Campbell meets two inventors, Buffy Price Co-founder and COO of Carbon Re, an AI and Climate Tech company spinout from UCL and Cambridge, and Professor Pete Coffey from UCL Institute of Ophthalmology and Founder of Tenpoint Therapeutics; both who are on that journey on how their inventions might improve our future world.
We also talk to Dr Anne Lane, CEO of UCLB to find out how UCLB finds the bright ideas which will improve lives, and what it takes to scale to a point where they are having true impact.
7
2/9/2024
Over a 15 year journey, UCLB spinout company Senceive Ltd became the world leader in the design, manufacture and supply of wireless enabled remote condition monitoring solutions for use in rail and construction applications. Recognition of the innovative and scalable nature of Senceive’s solutions to keep people and critical infrastructure safe, led to the company being acquired by Eddyfi in April 2021. In this podcast, Senceive’s now retired CEO Graham Smith and Dr Steven Schooling from UCLB discuss their experiences and learnings as they turned an early-stage university spinout into a highly successful and profitable commercial enterprise, which at exit generated strong returns for all shareholders
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8/22/2023
In the seventh episode of this podcast series, Jessica Bolton-Murray, Head of Project Management at UCLB, is in conversation with Tanel Ozdemir, Investment Manager for the UCL Technology Fund. The Project Management team at UCLB provides support and direction to any number of project at UCLB, working towards a commercial endpoint. The team have been providing bespoke project management services to all UCL Technology Fund projects, since inception in 2016 and have built a close working relationship, enabling them to move funded projects from proof of concept (POC) to licencing. Join them in this light-hearted discussion to find out how to access services, the challenges of POC, and what could be in store for the future
1
7/18/2023
From chronic diseases, the climate crisis, to social injustice, how are we tackling the biggest problems of the 21st century? As UCLB celebrates its 30th anniversary in 2023, this new monthly podcast series will explore how we have supported UCL academics to create impact across several areas, such as: medical research, patient healthcare, the environment, and our wellbeing in a contemporary society.
New episodes will be released every third Thursday of each month.
Soundtrack by Harry Penfold and Thomas Shearwood.
5
6/13/2023
In the third episode of this podcast series, UCLB Director of BioPharm, Dr Richard Fagan, is in conversation with UCL spinout Achilles Therapeutics’ (Achilles Tx) co-founder, Professor Charles Swanton. They will discuss Achilles Tx’s achievements and how TRACERx, the first study to track the evolution of cancer cells, will help us beat cancer.
2
3/8/2023
In the second episode of this podcast series, UCLB Senior Business Manager, Dr Mark Harding, explores UCL spinout Carbon Re's journey to market and their impact on reducing carbon emissions in heavy industries. He is joined by the co-founder and Chief Technology Officer of Carbon Re, Professor Aidan O'Sullivan.
7
2/8/2023
From chronic diseases, the climate crisis, to social injustice, how are we tackling the biggest problems of the 21st century? As UCL Business (UCLB) celebrates its 30th anniversary in 2023, this new monthly podcast series will explore how we have supported UCL academics to create impact across several areas, such as: medical research, patient healthcare, the environment, and our wellbeing in a contemporary society.
New episodes will be released every third Thursday of each month.
Soundtrack by Harry Penfold and Thomas Shearwood.
13
1/17/2023