Octopus is a new clinical trial for people living with progressive multiple sclerosis (MS), which is designed and run by the MRC Clinical Trials Unit at UCL. Thanks to its multi-arm multi-stage platform design, Octopus has the potential to transform the way treatments for progressive MS are tested. The trial is now open in the UK and will be recruiting participants for the next few years.
The podcast mini-series will explore the trial from different perspectives by talking to neurologists, MS experts and people affected by MS.
In Part 3, MS experts Dawn Lyle and Matthew Justin walk us through the journey that trial participants take when taking part in Octopus, from how to register your interest in the trial, to what to expect on your first visit.
3
11/1/2023
Octopus is a new clinical trial for people living with progressive multiple sclerosis (MS). Thanks to its multi-arm multi-stage platform design, Octopus has the potential to transform the way treatments for progressive MS are tested. The trial is now open in the UK and will be recruiting participants for the next few years.
The podcast mini-series will explore the trial from different perspectives by talking to neurologists, MS experts and people affected by MS.
Part 1 covers the treatment and research landscape of MS and the challenges of treating progressive MS. It features Jeremy Chataway, neurologist at National Hospital for Neurology and Neurosurgery at UCLH and Professor of Neurology at UCL, who is leading the Octopus trial. We also hear from Dawn Lyle, Lead Research MS Nurse, and Matthew Justin, MS Specialist, who are based at the Anne Rowling Regenerative Neurologic Clinic in Edinburgh.
4
10/19/2023
Immunotherapy drugs fight cancer by helping the immune system recognise and attack cancer cells. These drugs have revolutionised cancer treatment over the last decade, improving survival for many people with different types of cancer.
However, researchers are still unsure of the best way to give immunotherapy, which can come with unpredictable side effects.
In this episode, Clinical Fellow Sophie Merrick discusses how the REFINE trial hopes to address this problem, by testing if giving immunotherapy less frequently can still treat the cancer effectively, whilst improving the quality of life for patients, reducing side effects and costs.
Further information is available on the REFINE study page at www.mrcctu.ac.uk
For questions or feedback on the series, message us at mrcctu.engage@ucl.ac.uk
For more information and to access the transcript: https://bit.ly/3DgIDE2
0
7/18/2023
In the fourth episode of this podcast series, UCLB’s Director of Engineering and Physical Sciences, Dr Steven Schooling, is in conversation with Marina Santilli, UCLB Associate Director, Engineering & Physical Sciences about the development and scaling of UCLB’s express licensing platform e-lucid (https://e-lucid.com/). Early in her UCLB career, Marina recognised that there was a need for more effective tools to manage the licensing of lower value IP assets such as software and materials and in this podcast they discuss the journey from creating a minimum viable solution which addressed UCLB’s initial licensing needs through to the evolution of the e-lucid platform into a tool which has been adopted by some of the world’s leading universities, technology transfer and research organisations as they seek to enhance their impact outcomes.
14
4/19/2023
In this month’s episode of #MadeAtUCL we’re growing. Join us as we explore three unique perspectives on growth and how it can be both a positive and negative concept. We chat with Dr Michelle Heys and Dr Simbarashe Chimhuya and hear about their technical solution to newborn healthcare, with Dr Philip Pogge Von Strandmann about how we can reduce the growing levels of co2 in the atmosphere, and lastly with Dr Seb Coxon to learn how beards of medieval Germany can help us understand masculinity today.
Find out more and listen to the transcript here: www.ucl.ac.uk/made-at-ucl/podcasts/s2-ep8-growth
6
9/2/2021
In this month's episode of #MadeAtUCL, join us as we explore closeness and how proximity has changed over the past year. From designing new spaces that help us feel close from afar, to how researchers learnt about smartphones by living with their users, to how sounds of the rainforests thousands of miles way can help connect us to nature.
To find our more and access the transcript click here: www.ucl.ac.uk/made-at-ucl/podcas…ep7-getting-closer
2
9/2/2021
In this episode, #MadeAtUCL goes to Mars! We hear about the incredible UCL work that is helping to send a Rover (and maybe one day even a person) to the Red Planet as well as what we might find when we get there.
Act 1 - Prof Andrew Coates, Deputy Director (Solar System), at UCL’s Mullard Space Science Laboratory (MSSL) talks about the Rosalind Rover that launches to Mars in September 2022
Act 2 - Prof Ian Crawford, Honorary Senior Research Fellow Dept of Physics & Astronomy, at UCL's Faculty of Maths & Physical Sciences talks about possible life on Mars
Act 3 - Dr Iya Whiteley, a Space Psychologist and the Director of the Centre for Space Medicine at UCL’s Mullard Space Science Laboratory (MSSL) on what it takes to be chosen as an astronaut to go to Mars
Show notes and transcript on www.ucl.ac.uk/made-at-ucl/podcas…2-ep6-mission-mars
2
7/21/2021
Presented and edited by two UCL (University College London) graduates, Cassidy and Cerys, hear about research #MadeAtUCL on the costs of freedom.
In this episode we’re exploring the value of freedom, from the people who found it in the bleakest of circumstances to the ways in which we restrict our own freedom (and the freedom of others) without even realising it. Professor Virginia Mantouvalou shares her work on labour laws and explains how our legal system is creating situations that exploit vulnerable people. Dr Sarah J Young describes the experiences of Russian prisoners at Shlissel’burg and the memoirs she used to write her new book. And Dr Saheli Datta Burton tells us why we should be sceptical about our smart gadgets.
Transcript and show notes on www.ucl.ac.uk/made-at-ucl/podcas…2-ep5-cost-freedom
6
7/21/2021