22 items found in 3 pages
TINs Webinar: Nanoparticle formulations for therapeutic nucleic acid delivery
The development of mRNA based vaccines delivered in lipid nanoparticles (LNPs) has led to a surge of interest in the possible use of LNP mRNA formulation as a treatment for a range of other diseases. During this webinar, Prof. Steve Hart from the Department of Genetics & Genomic Medicine, will introduce nanoparticle technologies and the design and production of mRNA for their use in the development of therapeutics. This is part of the webinar series by the UCL Therapeutic Innovation Networks (TINs) to highlight UCL’s Research Infrastructure and Capabilities that enable effective translation of products toward patient/public benefit. The series aims to encourage multidisciplinary collaborations across departments. Academics from the UCL biomedical community are invited to share subjects of interest from their research expertise and interact with research fellows.
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8/2/2024
TINs Webinar: Formulations of RNAs and antibodies for pulmonary delivery
This session will unravel the complexities of developing inhaled formulations of biologics for the treatment of respiratory diseases such as severe asthma, viral infections, and cystic fibrosis. In her presentation, Dr Jenny Lam from the School of Pharmacy will give an overview of the use of particle engineering techniques and formulation strategies to overcome the delivery barriers. She will also introduce the spray drying technology, a versatile and scalable particle engineering technique that has been investigated for producing dry powder formulation of biologics with good stability (avoid cold-chain logistics) and aerosolisation properties for inhalation. This is part of the webinar series by the UCL Therapeutic Innovation Networks (TINs) to highlight UCL’s Research Infrastructure and Capabilities that enable effective translation of products toward patient/public benefit. The series aims to encourage multidisciplinary collaborations across departments.
22
5/23/2024
TINs Webinar: Overview of UCL Mass Spectrometry Science Technology Platform
In this presentation, Prof. Thalassinos from the Institute of Structural and Molecular Biology explored the functionalities of the UCL Mass Spectrometry Science Technology Platform, focusing on its mass spectrometry capabilities. He will also highlight several recent research projects that have been made possible due to this remarkable technology. This is part of the webinar series by the UCL Therapeutic Innovation Networks (TINs) to highlight UCL’s Research Infrastructure and Capabilities that enable effective translation of products toward patient/public benefit. The series aims to encourage multidisciplinary collaborations across departments. Academics from the UCL biomedical community are invited to share subjects of interest from their research expertise and interact with research fellows.
8
5/23/2024
UCL TINs Industry Club - Discovery Webinar
UCL is launching a major new initiative called TINs Industry Club, an opportunity for industry partners to engage the UCL Therapeutic Innovation Networks (TINs) to identify & address company R&D challenges, and to hear the latest UCL research for potential co-development. In this webinar, we showcased six areas of strength for the therapeutic modality Small Molecules that we think are ripe for collaboration.
8
5/23/2024
TINs Webinar: Antisense oligonucleotides as potential treatments for inherited retinal dystrophies
Antisense oligonucleotides (AONs) can be used to alter many aspects of gene expression, from splice isoform switching to reducing, or increasing, gene expression. The retina is an accessible part of the nervous system and is an ideal paradigm to study how AONs can be used to combat neurodegeneration. During this webinar, Prof. Mike Cheetham from the Institute of Ophthalmology will give an overview of AON design and show how they can be used as therapies for inherited retinal dystrophies (IRDs), from stem cell derived models of disease, to in vivo and clinical trials. This will exemplify the potential of AONs to treat genetic disease, and IRDs in particular. This is part of the webinar series by the UCL Therapeutic Innovation Networks (TINs) to highlight UCL’s Research Infrastructure and Capabilities that enable effective translation of products toward patient/public benefit. The series aims to encourage multidisciplinary collaborations across departments. Academics from the UCL biome
22
3/27/2024
TINs Webinar: Strategies to improve biologics manufacturing
During this webinar Prof. Paul Dalby will introduce examples of the kinds of research that is undertaken in Biochemical Engineering, in collaboration with academia and industry, to streamline the development and optimisation of manufacturing processes. This will also be an opportunity to explore the use of product engineering to improve their developability. Examples will cover a range of modalities including antibodies, cell therapies and viral vectors. This is part of the webinar series by the UCL Therapeutic Innovation Networks (TINs) to highlight UCL’s Research Infrastructure and Capabilities that enable effective translation of products toward patient/public benefit. The series aims to encourage multidisciplinary collaborations across departments. Academics from the UCL biomedical community are invited to share subjects of interest from their research expertise and interact with research fellows.
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1/10/2024
TIN PDS video interview with Dr Hassan Rashidi (Regenerative Medicine TIN)
This video highlights the work of 2020 Regenerative Medicine TIN PDS awardee Dr Hassan Rashidi, with a project titled “Dissecting the cross-talk between parenchymal and non-parenchymal derivatives within human pluripotent stem cell-derived 3D hepatospheres (3D Heps) using spatial transcriptomics”. Hassan comments on the importance of basic science in the translational pathway. The next Pilot Data Scheme funding opportunity for the Repurposing TIN is now open for applications until 24th October 2021. Learn more and apply: https://www.ucl.ac.uk/therapeutic-innovation-networks/funding-opportunities
191
10/22/2021
Dr Pilar Acedo video interview (Repurposing TIN)
This video highlights the work of 2020 Repurposing TIN PDS awardee Dr Pilar Acedo, with a project titled “Repurposing p53 reactivators for the treatment of pancreatic cancer”. Pilar highlights the value of working in a hospital at UCL to incorporate patient into her translational project. The next Pilot Data Scheme funding opportunity for the Repurposing TIN is now open for applications until 24th October 2021. Learn more and apply: https://www.ucl.ac.uk/therapeutic-innovation-networks/funding-opportunities
210
10/15/2021
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