10 items found in 2 pages
TARGIT-IORT surgical technique - TARGeted Intraoperative radioTherapy during lumpectomy for breast cancer
The original targeted intraoperative radiotherapy (TARGIT) for breast cancer using Intrabeam by Jayant S Vaidya in 2001 used in the TARGIT-A trial. Developed in collaboration with industry; INTRABEAM manufactured by Carl Zeiss. See http://www.ucl.ac.uk/~rmhkjsv/papers/targit.htm#disclaimer http://www.targit.org.uk Updates A few updates about the TARGIT technique using Intrabeam: 1. The shield on the posterior wall of the tumour bed is no longer used. 2. The posterior excision need not extend up to the pectoral fascia if adequate margin can be achieved without such an excision. 3. The transparent sterile cover for the Intrabeam is now available from the manufacturers. A few additional points that should be noted: 1. Conceptually, the fresh undisturbed tumour bed - the the empty, nearly spherical shell of normal breast tissue that surrounds the excised specimen - needs to be neatly in contact with the sphere of the Intrabeam applicator. NB the conical shaft of the applicator does no
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12/3/2021
New Insights from the TARGIT-A trial of radiotherapy during lumpectomy for breast cancer
New Insights from the TARGIT-A trial of radiotherapy during lumpectomy for breast cancer
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12/1/2021
New insights from the TARGIT-A trial 2021 16min
Invited talk at the Association of Breast Surgeons of India Conference, 26 Nov 2021
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12/1/2021
New insights from the TARGIT-A trial 5 min for NCRI 2021
TARGIT-IORT for breast cancer NCRI conference Nov 2021 - 5-Min Short talk
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12/1/2021
TARGIT-IORT radiotherapy during lumpectomy is better for patients 20min
Invited talk at the NHS Oncology Conference 23 Nov 2021
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12/1/2021
Environmental and Social Benefits of Intrabeam TARGIT IORT for Breast Cancer
Environmental and social benefits of the targeted intraoperative radiotherapy for breast cancer: data from UK TARGIT-A trial centres and two UK NHS hospitals offering TARGIT IORT. Nathan J Coombs, Joel M Coombs, Uma J Vaidya, Julian Singer, Max Bulsara, Jeffrey S Tobias, Frederik Wenz, David J Joseph, Douglas A Brown, Richard Rainsbury, Tim Davidson, Douglas J A Adamson, Samuele Massarut, David Morgan, Ingrid Potyka, Tammy Corica, Mary Falzon, Norman Williams, Michael Baum, Jayant S Vaidya BMJ Open 2016;6:e010703. http://bmjopen.bmj.com/content/6/5/e010703.full http://blogs.bmj.com/bmjopen/2016/05/09/radiotherapy-during-surgery-could-save-millions-of-travel-miles-and-tonnes-of-co2/ The use of TARGIT intraoperative radiotherapy for eligible patients with breast cancer significantly reduces their journeys for treatment and has environmental benefits: 5 million miles of travel, 170 000 woman-hours and 1200 tonnes of CO2 (a forest of 100 hectares) per year in the UK
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11/24/2018
Rethinking neoadjuvant chemotherapy for breast cancer
Rethinking Neoadjuvant Chemotherapy for breast cancer- Prof Jayant Vaidya Original BMJ paper is available at https://www.bmj.com/content/360/bmj.j... Full paper is available at http://discovery.ucl.ac.uk/10041365/ Full paper + Discussion is available at http://bit.ly/nactbmj2018full The BMJ Podcast https://soundcloud.com/bmjpodcasts/ne... Key messages Neoadjuvant chemotherapy is being increasingly used for breast cancer despite higher rates of local recurrence and no evidence of survival benefit, mainly because of the immediate and dramatic pathological responses seen with newer drugs The increased pathological response of the primary tumour in the breast does not translate into a survival benefit even when given in the adjuvant setting, challenging the paradigm of “window of opportunity” studies We must acknowledge that neoadjuvant chemotherapy may not be beneficial to breast cancer patients We should consider reducing the widespread use of neoadjuvant chemotherapy
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11/23/2018
TARGIT IORT treatment for breast cancer - Marcelle Bernstein, patients, expert panel,  and audience at the Royal Society
The Royal Society - Experts and patients discussing TARGIT IORT for breast cancer, 31 October 2018 http://www.targit.org.uk
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11/20/2018
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